Week 2 MLB Fantasy Baseball Preview: Must-Start Pitchers, Hitter Matchups & Weather Watch (March 31-April 6)

Complete Week 2 fantasy baseball breakdown featuring top two-start pitchers, optimal hitter matchups, weather concerns, and key scheduling insights for March 31-April 6.

MLB Fantasy Baseball Week 2: Complete Guide

The first full week of the 2025 MLB season brings critical decisions for fantasy managers as teams settle into their rotations. With most clubs playing 6-7 games, understanding the nuances of Week 2 matchups could give you an early edge in your league.

Key Week 2 Considerations:

  • Two-start pitchers dominate rotation schedules (mostly back-of-rotation arms)
  • Early-season weather concerns in northern ballparks
  • Cincinnati Reds and Philadelphia Phillies lead with 7-game weeks
  • First look at Sutter Health Park (Athletics' new home in Sacramento)

The full Week 2 schedule runs from Monday, March 31 through Sunday, April 6 with all 30 teams in action.

Starting Pitcher Analysis

Top 10 Two-Start Pitchers:

Rank Pitcher Team 1st Start 2nd Start Projection
1 Tyler Glasnow LAD vs. ATL @PHI 24-25 pts
2 Corbin Burnes ARI @NYY @WSH 23-24 pts
3 Cristopher Sánchez PHI vs. COL vs. LAD 22-23 pts
4 Bowden Francis TOR vs. WSH @NYM 21-22 pts
5 Ronel Blanco HOU vs. SF @MIN 20-21 pts

Notable Omissions:

  • Zack Wheeler (PHI) only gets one start (vs. COL)
  • Early-season workload management affects top aces

Weather Watch:

Northern cities like New York, Boston, and Chicago face potential rain/snow delays. Monitor:

  • Yankees-Rays (Bronx, 48° forecast)
  • Red Sox-Orioles (Boston, 45° with rain)
  • Cubs-Athletics (Sacramento, 52° but dry)

Hitter Matchup Ratings

Top 5 Teams for Hitters:

  1. Cincinnati Reds (7 games - 4 @MIL, 3 vs. TEX)

    • Elite: 10/10 overall rating on Friday vs. MIL
    • Play 3 games at hitter-friendly Great American Ball Park
  2. Detroit Tigers (6 games - 3 @SEA, 3 vs. CWS)

    • Face Mariners in cold Seattle weather, then weak White Sox rotation
  3. Philadelphia Phillies (7 home games)

    • Benefit from facing COL pitching staff at Citizens Bank Park

Park Factors to Watch:

  • Sutter Health Park (OAK): Initial data suggests pitcher-friendly dimensions with extra-base hit potential
  • Coors Field (COL): Always boosts offensive numbers, especially early in season
  • Great American Ball Park (CIN): Historically one of MLB's most hitter-friendly venues

Daily Fantasy Strategy

Best Stacking Opportunities:

  • Monday 3/31: Reds (vs. TEX) - Facing Kumar Rocker in debut
  • Wednesday 4/2: Phillies (vs. COL) - vs. Kyle Freeland at home
  • Saturday 4/5: Dodgers (@PHI) - Against softer part of Phillies rotation

Sleeper Picks:

  • OF James Outman (LAD): Hot spring, gets 2 games at hitter-friendly Philly
  • 2B Bryson Stott (PHI): 7 home games against weak COL/LAD pitching
  • SP Garrett Crochet (CWS): Increased velocity, gets BAL in cold Chicago

Final Thoughts

Week 2 presents unique challenges with unpredictable weather and rotations still settling. Focus on:

  1. Two-start pitchers with favorable matchups
  2. Hitters in warm-weather venues or hitter-friendly parks
  3. Teams playing 7 games (CIN, PHI)
  4. Early-season bullpen usage trends

Remember: These are early-season projections. Be ready to adjust as real-game data emerges.

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